2024 Rome, Italy

I-05 Miro Eigenmann
PBPK modeling approach to study the impact of lymph flow on the biodistribution of therapeutic antibodies
Wednesday 10:20-11:40
I-15 Saskia Fuhrmann
Generic PBPK model to predict preclinical and clinical PK of antibodies
Wednesday 10:20-11:40
I-25 Ignacio Gonzalez-Garcia
Assessment of in vitro dissolution specifications based on an IVIVC and in vivo bioequivalence criteria
Wednesday 10:20-11:40
I-36 Nina Hanke
Physiologically-based Pharmacokinetic Modeling of Rifampin Drug-Drug Interactions with Midazolam and Digoxin
Wednesday 10:20-11:40
I-45 Xiao Hu
Population pharmacokinetic analysis of fampridine in Japanese patients with multiple sclerosis in a Phase 3 study
Wednesday 10:20-11:40
I-53 Masoud Jamei
Time variation in the fractional contribution of an enzyme to elimination of a victim drug can explain differences in DDI susceptibility following single and multiple dosing
Wednesday 10:20-11:40
I-56 Jong Bong Lee
Predicted versus experimental permeability data for incorporation into GastroPlus™ for modelling and simulations
Wednesday 10:20-11:40
II-15 Kathryn Ball
Prediction of food effect in the Chinese population using a PBPK model developed in a Caucasian population
Wednesday 15:10-16:30
II-31 Hannah Britz
Physiologically-Based Pharmacokinetic (PBPK) Modeling of the Dronedarone Drug-Drug Interaction with Digoxin
Wednesday 15:10-16:30
II-49 Yumi Cleary
Physiologically –based pharmacokinetic (PBPK) and population PK (PPK) modeling for basimglurant - assessment of predicted variability by the PBPK model and its utility
Wednesday 15:10-16:30
II-57 André Dallmann
Validation of a Population Physiologically-Based Pharmacokinetic Model for Pregnant Women
Wednesday 15:10-16:30
II-60 Miné De Kock
Pharmacokinetics of Sulfadoxine and Pyrimethamine for intermittent preventive treatment of malaria during Pregnancy and after delivery.
Wednesday 15:10-16:30
II-62 Mailys De Sousa Mendes
A physiologically based pharmacokinetic model for a drug metabolized by several CYP450 during pregnancy
Wednesday 15:10-16:30
III-08 Gaohua Lu
A Novel Mechanistic Approach to Predict the Steady State Volume of Distribution (Vss) using the Fick-Nernst-Planck Equation
Thursday 10:05-11:30
III-29 Morris Muliaditan
Prediction of the exposure of anti-tuberculosis drugs in lung tissue: implications for dose selection
Thursday 10:05-11:30
III-37 Andrés Olivares-Morales
Combining population with physiologically-based pharmacokinetic (PBPK) models for oral drug absorption: Predicting the segmental bioavailability differences of R-oxybutynin and its main metabolite using a middle out approach.
Thursday 10:05-11:30
III-63 Christian Radke
Development of a PBPK approach to predict the pharmacokinetics in patients with sepsis
Thursday 10:05-11:30
IV-26 Donato Teutonico
Whole-body PBPK/PD modelling of ciprofloxacin and its anti-bacterial activity
Thursday 14:40-16:00
IV-30 Huybrecht T'jollyn
Pharmacokinetics of galantamine in plasma and brain for different intranasal formulations: an experimental in vivo study
Thursday 14:40-16:00
IV-38 Ken-ichi Umehara
Assessment of DDI potential of ruxolitinib (INC424), a dual substrate of CYP3A4 and CYP2C9, using a verified PBPK model to support submissions to Health Authorities
Thursday 14:40-16:00
IV-53 Ulrika Wählby Hamrén
Pharmacokinetics of the inhaled selective glucocorticoid receptor modulator AZD5423 following inhalation using different devices
Thursday 14:40-16:00